MCQ-465

 

Answer: e) Methyl salicylate

Methyl salicylate is used as an external analgesic as an over the counter medicine.

MCQ-224

 

Answer: c) Valproate Sodium.

Valproate and Carbamazepine are the drugs that are used to treat epilepsy or bipolar disorder is associated with spina bifida or other birth defects when consumed in pregnancy.

MCQ-223

 

Answer: d) Hydromorphone.

Hydromorphone is strong semi-synthetic µ-opioid agonist.

 

MCQ-222

 

Answer: b) Nalbuphine.

Nalbuphine is semisynthetic mixed agonist-antagonist opioid modulator of phenanthrene or morphinan series.

MCQ-221

 

Answer: d) Dofetilide.

Dofetilide is class III antiarrhythmic drug which is Potassium Channel blocker, is used orally in the form of capsules in arrhythmia.

MCQ-220

 

Answer: c) Entacapone.

Entacapone is a selective and reversible COMT inhibitor which inhibits metabolism of Levodopa thus increases plasma levels of Levodopa which is needed for more constant dopaminergic stimulation that is required to reduce the signs and symptoms presented in Parkinson’s disease.

MCQ-219

 

Answer: b) Metronidazole

MCQ-218

 

Answer: d) a,b & c

Colesevelam, colestipol and colestyramine increases the binding of bile acids in the intestine, interfering with its absorption, as a result of which demand for bile acids increases for which cholesterol is converted to bile acid in the presence of 17 α hydroxylase, this causes increased demand of cholesterol in the liver cells, this increases the activity of HMG-CoA reductase which increases hepatic LDL receptors sensitivity, thus decreases serum LDL cholesterol.

MCQ-217

 

e) Acetohexamide.

MCQ-216

 

Answer: b) Diethylstilbestrol

Diethylstilbestrol is non-steroidal estrogen medication that was used in past for variety of indications.

 

MCQ-215

 

 

b) Cyclosporin

The use of Cyclosporine with Warfarin alters the effect of both drugs, the dose adjustment is required while prescribing both these drugs on the basis of INR.

MCQ-214

 

Answer: Cytarabine

MCQ-213

 

Answer: a) Amprenavir

Amprenavir is a protease inhibitor used to treat HIV infections.

MCQ-212

 

Answer: d) Bisacodyl

Bisacodyl is stimulant laxative which is a derivative of triphenylmethane.

MCQ-211

 

Answer: a) Gemtuzumab

MCQ-210

 

Answer: d) Thiabendazole

MCQ-209

 

a) Ketoconazole

MCQ-208

 

Answer: d) Metronidazole.

MCQ-207

 

Answer: d) Nitroglycerin

MCQ-206

 

Answer: c) Clofazimine.

Clofazimine together with dapsone and Rifampicin is used to treat leprosy.

MCQ-205

 

Answer: c) Isoniazid.

Isoniazid is isonicotinic acid hydrazide which is used as bactericidal to fast growing mycobacteria and bacteriostatic to slow growing mycobacteria in tuberculosis.

MCQ-204

 

Answer: e) Polymyxins

Polymyxin B and E is also known as colistin, they are used against gram negative organisms. They are part of broader class of molecules known as nonribosomal peptides.

MCQ-203

 

 

Answer: a) Methotrexate

MCQ-202

 

Answer: d)Aztreonam

Aztreonam is in the monobactam family of medications; those who are allergic to beta lactam penicillins are less allergic to Aztreonam. It is safe to use in pregnancy. It results in bacterial death by inhibiting cell wall synthesis by bacteria.

MCQ-201

 

Answer: d) a & b

Strongyloidiasis is a parasitic infection caused by roundworm or nematode known Strongyloides stercolaris. Albendazole and thiabendazole can be used for this parasitic infection. The dose of thiabenddazole is 25mg/kg twice daily for 5 days can be given maximum dose is 400mg generally.

MCQ-200

 

Answer: c) Guaifenesin.

Guaifenesin is used as an expectorant, it clears up throat and chest and making it easier to cough. It is used to treat congestion caused by allergies, infections or common cold.

MCQ-199

 

Answer: d) Sodium picosulfate.

Sodium picosulfate is contact stimulant laxative which is used to relieve constipation or the prepare the large bowel before colonoscopy or surgery.

MCQ-198

 

Answer: d) Rasagiline

Parkinson’s disease is caused by the death of the cells that produce dopamine. MAO type B specifically causes metabolism of dopamine. Rasagiline inhibits Type B MAO irreversibly thus reserving the stores of dopamine in the brain.

MCQ-197

 

Answer: a) Reserpine

Reserpine inhibits the uptake and reduces the stores of neurotransmitters such as norepinephrine, dopamine, serotonin and histamine in the synaptic vesicles of neurons.

MCQ-196

 

Answer: b) Clonidine

Clonidine crosses blood brain barrier, it acts as alpha 2 adrenergic agonist and treats blood pressure by decreasing peripheral vascular resistance.

MCQ-195

 

Answer: c) Methyldopa