MCQ-152

 

Answer: d) Tranylcypromine.

Tranylcypromine is non-hydrazine monoamine oxidase inhibitor used as antidepressant, it has diminished propensity to cause hepatotoxicity.

MCQ-151

 

Answer: c) Kaolin.

MCQ-150

 

Answer: c) Pegaptanib sodium.

Age related macular degeneration is a medical condition that may result in blurred or no vision in the center of the visual field. Pegaptanib sodium is vascular endothelial growth factor inhibitor that works by inhibiting growth if blood vessels within the eye and thus prevents leakage and swelling.

MCQ-149

 

Answer: d) Tacrine.

MCQ-148

 

Answer: b) Somatropin.

MCQ-147

 

Answer: b) Danazol.                 

Danazol is a synthetic androstane steroid with a weak antigonadotropin activity via acting through pituitary axis. It is used in the treatment of hereditary angioedema, fibrocystic breast disease and endometriosis.

MCQ-146

 

Answer: a) Docusate                

Docusate is surfactant laxative, it reduces tension of the oil water interface of the stool by incorporating more water and fat in the stool, making it softer and easier to pass.

MCQ-145

 

Answer: b) Latanoprost.

MCQ-144

 

Answer: b) Diphenoxylate hydrochloride.

Diphenoxylate hydrochloride is used to treat diarrhea in adults, it is used in combination with atropine to prevent drug abuse.

MCQ-143

 

Answer: c) Levomethadyl acetate.

Levomethadyl acetate is synthetic opioid agonist is used in the management of opioid dependence when methadone or buprenorphine fail to respond.

MCQ-142

 

Answer: c) Zolpidem.

 Zolpidem is a nonbenzodiazepine used for short term in the treatment of insomnia.

MCQ-141

 

Answer: c) Adefovir dipivoxil.

Adefovir is an orally administered nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B.

MCQ-140

 

Answer: b) Raloxifene.

Raloxifene is a selective estrogen receptor modulator with mixed agonist and antagonist effect on estrogen receptors. It is estrogenic in bones and antiestrogenic in breast and uterus.

MCQ-139

 

Answer: a) Vitamin D

 

MCQ-138

 

Answer: b) Cephalosporins.

Combination of two antibiotics increases nephrotoxicity.

MCQ-137

 

Answer: d) Cyclopentolate hydrochloride.

A mydriatic is an agent that causes dilation of the pupil. Cyclopentolate hydrochloride is muscarinic antagonist which is usually used in the examination of pediatric eye.

MCQ-136

 

Answer: c) Flucytosine.

 

MCQ-135

 

Answer: a) Fluvastatin.

Fluvastatin is inhibitor of liver enzyme HMG-CoA reductase which is involved in the cholesterol synthesis.

MCQ-134

 

Answer: c) Auranofin.

Auranofin is a gold salt considered by WHO as an antirheumatic agent.

MCQ-133

 

Answer: d) Betamethasone

Betamethasone is a long acting glucocorticoid having elimination half-life of about 36-54 hours.

 

MCQ-132

 

Answer: d) Acemetacin

Acemetacin is glycolic acid ester of Indomethacin, cleavage of glycolic acid ester turns Acemetacin to Indomethacin.

 

MCQ-131

 

Answer: a) Niacin

The deficiency of Vitamin B3 (Niacin) causes pellagra which is characterized by inflamed skin, sores in mouth, dementia and diarrhea. The skin first affected is the one exposed to sunlight or friction or both.

MCQ-130

 

Answer: c) Naproxen

Naproxen is propionic acid derivative used as an NSAID.

 

MCQ-129

 

Answer: c) Benztropine.

Benztropine is used in the treatment of extrapyramidal side effects due to antipsychotic drugs.

MCQ-128

 

Answer: d) 45mEq/kg.

MCQ-127

 

Answer: d) Nortriptyline.

MCQ-126

 

Answer: b) Lorazepam.

Lorazepam in small dose is useful in treating dizziness during an episode of vertigo in Meniere’s disease.

MCQ-125

 

Answer: e) All of the above.

MCQ-124

 

Answer: b) Riboflavin.                            

Riboflavin also known as Vitamin B2 is water soluble vitamin is involved in cellular respiration, it also converts carbohydrates to glucose, and also metabolizes fats and proteins to yield energy.

MCQ-123

 

Answer: b) Indinavir.

Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS. It is soluble white powder administered orally in combination with other antiviral drugs. The drug prevents protease from functioning normally.

MCQ-122

 

Answer: c) Citalopram

Premenstrual Dysphoric Disorder is more severe than PMS, as it is characterized by severe irritability, anxiety or depression that begins a week or two before onset of menstruation and lasts three days on the onset of menstrual cycle.

 

MCQ-121

 

Answer: a) Tegaserod.

Tegaserod is 5-HT4 agonist which was used in the treatment of irritable bowel syndrome and constipation before 2007; it was withdrawn from the market because of its severe cardiovascular effects.

MCQ-120

 

Answer: e) Mirtazapine.

Mirtazapine is third generation heterocyclic atypical antidepressant which works by inhibition of some adrenergic, serotonin receptors as well as antihistaminic properties.

MCQ-119

 

Answer: a) Carglumic acid.

Carglumic acid is an orphan drug which is used in the treatment of hyperammonaemia due to N-acetylglutamate synthase deficiency.

 

MCQ-118

 

Answer: c) Mercaptamine.

Nephropathic cystinosis is lysosomal storage disease which affects, infants, adolescents and adults. The adult form is non-specific. It is characterized by corneal crystals causing photophobia and renal disease causing excessive urination with excessive excretion of amino acids and carbohydrates. Mercaptamine (cysteamine) is used in the treatment of cystinosis and is available in the capsules and in eye drop formulations.

MCQ-117

 

Answer: b) Chlorpromazine

  Phenothiazine

 

 

Chlorpromazine- Aliphatic Phenothiazine

MCQ-116

 

Answer: d) Laronidase.

Laronidase is used to treat mucopolysaccharide storage disorders (specifically mucopolysaccharidosis 1 or Hurlers syndrome) caused by deficiencies of alpha-L-iduronidase. Reduced or absent a-L-iduronidase activity results in the accumulation of the GAG substrates, dermatan sulfate and heparan sulfate, throughout the body and leads to widespread cellular, tissue, and organ dysfunction.

MCQ-115

 

Answer: c) Betahistidine.

Betahistine is a strong antagonist of the histamine H₃ receptor and a weak agonist of the histamine H₁ receptor.