Short Acting beta 2 Agonist

Answer: b & d

Terbutaline (Bricanyl) and Salbutamol (Albuterol) are short acting beta 2 agonists.

NSAID from Anthranilic Acid Group

Answer: c- Mefenamic acid

Mefenamic acid is an NSAID from anthranilic acid group, which is used to treat mild to moderate pain, also pain from menstruation, and headache associated with menstruation.

HMG-CoA Reductase Inhibitor

Answer: c- Atorvastatin

Atorvastatin is a competitive inhibitor of enzyme HMG Co-A Reductase.  HMG Co-A is reduced to mevalonate in the presence of enzyme HMG Co-A reductase, which is a rate limiting step in the biosynthesis of cholesterol, thus the inhibition of HMG Co-A reductase helps lower serum cholesterol levels. Atorvastatin lowers serum LDL and triglycerides levels and slightly increases serum HDL levels.

Fibrates

Answer: e- None of these answers.

Anion exchange resin

Answer: e-a & d

Both Colestyramine and Colestipol are bile acid sequestrants which are anion exchange resins used to lower plasma cholesterol levels.

Panic Disorder

 Answer: d- Alprazolam

Alprazolam binds to GABA A receptor, GABA which is an inhibitory neurotransmitter, the binding to this results in calming effect, chiefly it is used to treat anxiety. The influx of chloride ions takes place after the binding of Alprazolam to the GABA receptor and thus prevents depolarization.

Proteolytic Enzyme Inhibitor

Answer: d- Aprotinin

Proteolytic enzymes are those enzymes that break down proteins to their smaller fragments (peptides) into their components, amino acids. Aprotinin is a small bovine pancreatic trypsin inhibitor (BPTI). Aprotinin is a competitive inhibitor of trypsin, chymotrypsin, plasmin and Kallikrein.

Fibrinolytic agent

Answer: c- Alteplase

In a systemic circulation Alteplase binds to fibrin in a thrombus and causes fibrinolysis.

Glycoprotein IIb/IIIa Inhibitors

Answer: d- Clopidogrel

Clopidogrel inhibits the binding of adenosine diphosphate (ADP) binding to P2Y12 receptor on platelets, hence inhibits ADP mediated glycoprotein IIb/IIIa activation and thus prevents platelet adhesion and aggregation.

Synthetic pentasaccharide

Answer: e- Fondaparinux

Fondaparinux is a synthetic pentasaccharide which indirectly inhibits factor Xa, it works through antithrombin factor III, but comparing to heparin it is selective to factor Xa.

Oral Anticoagulant

Answer:  d- Acenocoumarol

Acenocoumarol is coumarin derivative which is used as an oral anticoagulant.