Answer: e) Amrinone
Amrinone is pyridine
phosphodiesterase 3 inhibitor which is used for short term in the management of
congestive heart failure. It increases cardiac contractility and also acts as a
vasodilator.
It is a place where you can improve your pharmacy skills, with the expertise in pharmaceutical calculations and also to the other subjects in pharmacy.
Answer: e) Amrinone
Amrinone is pyridine
phosphodiesterase 3 inhibitor which is used for short term in the management of
congestive heart failure. It increases cardiac contractility and also acts as a
vasodilator.
Answer: c) Dantrolene
Malignant hyperthermia is a type
of severe reaction due to exposure to generalized anaesthetic resulting in high
grade fever, muscle rigidity, high blood potassium, fast heart rate and muscle
breakdown. Dantrolene is used in malignant hyperthermia as it causes relaxation
of muscles and treating the muscles spasms and stiffiness by decreasing calcium
in muscle cells.
Answer: b) Flumazenil.
Flumazenil is benzodiazepine antagonist
worked via competitive inhibition in benzodiazepine overdose. It works as GABA
A receptor antagonist.
Answer: c) Suxamethonium
Suxamethonium is depolarizing
muscle relaxant that works as acetylcholine receptor agonist, it does not allow
binding of the acetylcholine to the receptor and results in skeletal muscle relaxation.
Its use is limited for short term muscle relaxation in anesthesia and intensive
care for endotracheal intubation.
Answer: a) Drotrecogin alfa
Drotrecogin alfa does not improve mortality in severe sepsis
or septic shock but increases the bleeding risks, because of being anti-inflammatory,
profibrinolytic and anti-thrombotic properties.
Answer: d) Halothane
Halothane is volatile liquid having sweet chloroform like odor
and is used as a generalized anaesthetic.
Answer: c) Entacapone
Entacapone is Catechol-O-methyl transferase inhibitor which
is used as adjunct to levodopa, it inhibits levodopa metabolism in the periphery,
increasing plasma levodopa levels and dopaminergic stimulation, thus reducing
signs and symptoms in Parkinson’s disease.
Answer: c) Silver sulfadiazine.
Silver sulfadiazine is topical antibiotic used in partial
thickness and full thickness burns to prevent spread of infection.
Answer: a) Azelaic acid
Azelaic acid is available as 15%, 20 % cream to treat mild
to moderate acne. It works by killing bacteria, as well as it decreases the
production of keratin which is a natural substance involved in the growth of
acne bacteria.
Answer: d) Hydrogen Peroxide.
Vincent’s disease is a dental illness characterized by foul odor
to the breath and bleeding gums caused by bacterium Fusobacterium fusiforme.
Hydrogen peroxide mouth wash is used as an oxidizing agent in killing anaerobic
bacteria in acute necrotising ulcerative gingivitis.
Answer: e) Azelastine
hydrochloride.
Azelastine is second generation antihistamine which is used
in the form of nasal spray in the treatment of allergic rhinitis.
Answer: b) Aluminium acetate.
Wetness in otitis externa causes bacterial and fungal growth
characterized by pain and inflammation. Aluminium acetate acts as astringent to
the cause defined and treats the infection and relieves pain and inflammation.