Pharma BCQ- Cold Remedy

ANSWER:  B

DESCRIPTION

Cold remedy is a combination of an analgesic, sedating anti-histamine, nasal decongestant and ascorbic acid. The Beecham’s Hot Lemon and Honey sachet is  a cold preparation containing paracetamol, ascorbic acid and a nasal decongestant phenylephrine.

Pharma BCQ- Clarinase

ANSWER: D

DESCRIPTION

Clarinase contains Loratadine which is second generation anti-histamine and pseudoephedrine which is nasal decongestant. The therapeutic alternative is Cirrus which contains Cetirizine which is second generation anti-histamine and a nasal decongestant that is pseudoephedrine.

Pharma BCQ- Bronchodilation

ANSWER: A

DESCRIPTION

Adrenaline causes bronchodilation, and is used in anaphylactic shock. Kinins, Prostaglandin E2 and Histamine are inflammatory mediators. In allergic reactions, these inflammatory mediators cause bronchoconstriction. Guaifenesin is expectorant, which promotes the expulsion of the mucus.

Pharma BCQ- Digoxin

ANSWER: E

DESCRIPTION

Digoxin is a cardiac glycoside, which is used in heart failure. It decreases the conduction of AV node and is so used in atrial fibrillation. It has a long half-life, so it is used once daily and is excreted by kidneys, so in renal impaired patients the dose is low.  It increases the contraction of myocardial cells, so it is used in heart failure. Arrhythmias, atrial tachycardia occur due to digoxin toxicity. The chances of toxicity are more in electrolyte disturbances such as hypercalcaemia, hypokalaemia and hypomagnesaemia.

Pharma BCQ- Unstable Angina

ANSWER: B

DESCRIPTION

The management of unstable angina is to use anti-platelet drugs such as Aspirin and Clopidogrel, in order to reduce the chances of Myocardial infarction and death. Isosorbide dinitrate can also be used, as it is a vasodilator, it improves the blood supply to cardiac cells. Exercise stress test cannot be performed in unstable angina.

Pharma BCQ- PUD

ANSWER: B

DESCRIPTION

Omeprazole should not be used in breast feeding, neither to be used in gastric carcinoma, as it worsens the condition. It is used as a triple therapy in the eradication of Helicobacter pylori infection.

Pharma BCQ- Losec MUPS

ANSWER: B

DESCRIPTION

Losec MUPS contain omeprazole; it contains dispersible tablets that can be added in water or fruit juice. It cannot be chewed.