Pharma BCQ- Sirolimus

ANSWER: C

DESCRIPTION
Sirolimus is calcineurin inhibitor which acts as immunosuppressant. It is used in prophylaxis of organ rejection in kidney allograft recipients. It can be given with ciclosporin initially, as ciclosporin is severely nephrotoxic, renal function is needed to be monitored when treatment is carried out with ciclosporin.

Pharma BCQ- Seborrhoeic dermatitis

ANSWER: A

DESCRIPTION

Dandruff is a form of seborrhoeic dermatitis. The use of shampoo containing coal tar can be used, but it is not the first choice. Betnovate lotion contains betamethasone, which is useful in severe dandruff.

Pharma BCQ- Phenylephrine

ANSWER: A

DESCRIPTION

Phenylephrine which is a sympathomimetic causes increase in heart rate and blood pressure; it should not be used systemically in glaucoma, hypertension, hyperthyroidism, ischemic heart disease and diabetes mellitus. However, topically it can be used in the above mentioned conditions as nasal decongestant. Both topical and systemic preparation is contraindicated in patients taking monoamine oxidase inhibitors, as it may aggravate the hypertensive crisis.

Pharma BCQ- Contact Lens Wear

ANSWER: A

DESCRIPTION

Phenergen contains anti-histamine promethazine and Valium contains benzodiazepine that is diazepam, both of which reduces blinking of the eye and causes dry eyes. Cilest contains combined oral contraceptive which causes corneal and eyelid edema.

Pharma BCQ- ISD

ANSWER:B

DESCRIPTION

Infantile seborrhoeic dermatitis or cradle cap is a type of eczema which is common in infants. It occurs in first three months of life and resolves spontaneously within a year. The use of almond oil, clove oil, baby oil or olive oil into the scalp leaving overnight and washing the following day can help treat cradle cap.

Pharma BCQ-Stemetil

ANSWER: D

DESCRIPTION

Stemetil is proprietary preparation of prochlorperazine, which is used in vertigo and labyrinthine disorders. There is no contraindication for the use of prochlorperazine with paracetamol.  Stemetil is available in the form of tablets, syrup and injection.

Pharma BCQ- Simvastatin

ANSWER: A

DESCRIPTION
Simvastatin is a statin given at night, any sign of muscle weakness with the use of drug should be promptly reported. The patients taking statins are advised to avoid fatty diet and add more fibre to the diet.

Pharma BCQ- Ivabradine

ANSWER: E

DESCRIPTION
Ivabradine is used in angina with normal sinus rhythm. It is contraindicated in acute myocardial infarction, severe bradycardia ( heart rate lower than 60 beats/ minute), unstable angina or pace maker. Ivabradine causes blurred vision as a side-effect.

Pharma BCQ- Suboxone

ANSWER: A

DESCRIPTION
Suboxone contains buprenorphine which is opioid partial agonist and naloxone. It is used as perioperative analgesia and as adjunct in the treatment of opioid dependence. It is available as sublingual tablets. The side effect of opioids is drowsiness.























;

Pharma BCQ- Thrombocytopenia

ANSWER: B

DESCRIPTION
Heparin causes immune mediated thrombocytopenia, which arise 5- 10 days after the administration of heparin, so it is recommended to check platelet count before starting treatment with heparin. When heparin is used for treatment, platelet count is monitored on daily basis, and if spontaneous bleeding occurs with the use of heparin, it must be stopped. Factor VIII is required in the treatment and prophylaxis of hemorrhage associated with hemophilia.

Pharma BCQ- Antibacterials 2

ANSWER:D

DESCRIPTION
Fusidic acid is a narrow spectrum antibacterial, and it requires hepatic clearance, hence no caution is needed in renal impairment.

Pharma BCQ- Antibacterials

ANSWER : C

DESCRIPTION
Gentamicin is an aminoglycoside which is associated with nephrotoxicity and ototoxicity, when it is used systemically, more frequent evaluation of the drug serum concentration is recommended in patients with compromised renal function.

Pharma BCQ- Raynaud's Phenomenon

ANSWER: D

DESCRIPTION
 Atenolol which is a beta adrenoceptor blocker, should be avoided as it may cause coldness of the extremities, which may worsen the Raynaud's phenomenon.

Pharma BCQ- Hypertension evaluation

ANSWER: C

DESCRIPTION
Long standing hypertension causes various cardiovascular complications such as myocardial infarction, stroke and peripheral vascular diseases, so the complications of hypertension can be evaluated by electrocardiogram, chest radiographs, renal or hepatic function tests and  via. retinal examination.

Rheumatoid arthritis

ANSWER: b

DESCRIPTION
Cytokine inhibitors such as infliximab, etanercept, adalimumab are disease modifying anti-rheumatic drugs which can be used in addition with methotrexate in flare-up of rheumatoid arthritis.